Medical tubing Medical tubing CPAP Tubing Film

Versaflex™ & Versalloy™ Specialty Engineered Materials Thermoplastic Elastomers for Healthcare Applications Delivering specialized thermoplastic elastomer (TPE) solutions for demanding healthcare applications, Avient has performance-grade materials that are approved for USP VI, ISO 10993-4 and 10993-5. Common healthcare applications include medical tubing, gaskets and stoppers, bags, bottles and films, grips, handles and medical devices. VERSAFLEX™ HC MEDICAL TUBING SERIES • Improve extrusion rates, achieve high service temperature performance or increase clarity in medical tubing • Meet biopharmaceutical needs for weldability and minimize extractables during processing VERSALLOY™ HC SERIES • Obtain better flow in long, thin paths and lower shrink rates versus typical TPVs with our alloys, made with Santoprene™ TPV • Color easily and obtain a smooth tactile feel VERSAFLEX™ HC GASKETS & STOPPERS SERIES • Achieve no coring, good puncture and resealability in static stoppers • Meet low COF and low stiction requirements in dynamic seals VERSAFLEX™ CL E SERIES • Increase clarity and flexibility in bags, bottles and films • Mitigate risk with plasticizer-free formulations for film extrusion • Deliver excellent odor & O 2 barrier performance for film extrusion INDUSTRY BULLETIN TPE HEALTHCARE PRODUCT SELECTOR GUIDE Versaflex™ HC MT Series Versaflex™ HC MT222 Clear 66A 0.88 14 - 334 2.30 629 4.34 898 6.19 430 220 36 ✔ ✔ High clarity, without plasticizers Versaflex™ HC MT224 Clear 75A 0.89 19 - 468 3.23 773 5.33 1360 9.40 530 321 56 ✔ ✔ Versaflex™ HC MT226 Clear 84A 0.88 20 - 606 4.17 885 6.10 1600 11.00 600 433 76 ✔ ✔ Versaflex™ HC MT317 Clear 68A 0.89 17 69 450 3.10 660 4.55 870 6.00 470 221 39 ✔ ✔ Very high service temperature Versaflex™ HC BT218 Natural 67A 0.89 19 69 381 2.60 683 4.70 1186 8.20 608 - - ✔ ✔ Weldable, kink resistant Versaflex™ HC Gaskets & Stoppers Series Versaflex™ HC 2110-35N Natural 34A 0.90 19 47 145 1.00 261 1.80 400 2.76 620 97 17 ✔ ✔ Good resealing Versaflex™ HC 2110-43N Natural 43A 0.98 12 46 134 0.92 368 2.54 723 4.98 710 - - ✔ ✔ Good compression set Versaflex™ HC 2110-57B Black 59A 1.01 20 37 369 2.54 558 3.85 537 3.70 350 147 26 ✔ ✔ Low stiction Versaflex™ CL E Series Versaflex™ CL E85 Clear 84A 0.90 20 72 752 5.18 1160 8.00 1550 10.70 450 433 76 ✔ ✔ High clarity, without plasticizers; E95 also offers excellent odor & O 2 barrier Versaflex™ CL E90 Clear 90A 0.90 27 73 1000 6.89 1230 8.50 1830 12.60 57 - - ✔ ✔ Versaflex™ CL E95 Clear 95A 0.90 38 71 1680 11.60 1730 11.90 2500 17.20 580 720 126 ✔ ✔ Versaflex™ HC 3810 Series Versaflex™ HC 3810-20N Natural 20A 0.88 16 54 123 0.80 185 1.30 342 2.40 650 - - ✔ - Formulated without animal derivatives, excellent colorability, translucent Versaflex™ HC 3810-30N Natural 30A 0.89 18 58 170 1.20 245 1.70 459 3.20 680 - - ✔ - Versaflex™ HC 3810-40N Natural 40A 0.88 19 59 191 1.30 275 1.90 506 3.50 670 - - ✔ - Versaflex™ HC 3810-50N Natural 50A 0.89 21 61 264 1.80 366 2.50 699 4.80 690 - - ✔ - Versaflex™ HC 3810-60N Natural 60A 0.88 24 65 459 3.20 594 4.10 790 5.40 510 - - ✔ - Versaflex™ HC 3810-70N Natural 70A 0.88 28 67 535 3.70 684 4.70 1000 6.90 570 - - ✔ - Versaflex™ HC 3810-80N Natural 80A 0.88 30 67 689 4.80 869 6.00 1390 9.60 620 - - ✔ - Versaflex™ HC 3810-90N Natural 90A 0.88 27 89 1087 7.50 1350 9.30 1890 13.00 570 - - ✔ - Versalloy™ HC 9210 Series Versalloy™ HC 9210-45N Natural 45A 0.89 19 39 160 1.10 320 2.20 484 3.33 480 100 18 - ✔ Smooth surface aesthetics Versalloy™ HC 9210-55N Natural 53A 0.89 20 44 208 1.44 335 2.31 580 4.00 610 120 21 - ✔ Versalloy™ HC 9210-70N Natural 70A 0.89 23 53 356 2.45 510 3.52 780 5.38 590 180 32 - ✔ Versalloy™ HC 9220 Series Versalloy™ HC 9220-70 Natural 70A 0.95 17 51 453 3.12 - - 643 4.43 265 208 36 ✔ ✔ ExtrudableVersalloy™ HC 9220-80 Natural 80A 0.94 18 59 553 3.67 777 5.36 945 6.52 415 208 36 ✔ ✔ Versalloy™ HC 9220-90 Natural 90A 0.94 25 55 1030 8.13 1350 9.33 1945 13.45 620 400 70 ✔ ✔ Standard Healthcare Grades Versaflex™ G2705N Natural 60A 0.88 - - - - 528 3.64 670 4.62 470 - - ✔ ✔ Natural, high strength Versaflex™ CL 2242 Clear 43A 0.89 23 - 152 1.05 294 2.02 731 5.00 780 124 22 ✔ ✔ High clarity, boilable Versaflex™ CL 2250 Clear 50A 0.89 20 - 220 1.52 337 2.32 827 5.70 770 140 25 ✔ ✔ Versaflex™ OM Series Versaflex™ OM 1040X Natural 42A 0.92 22 - 180 1.24 301 2.08 504 3.47 580 100 18 ✔ ✔ ABS/PC overmoldVersaflex™ OM 3060 Clear 59A 0.90 33 - 420 2.90 360 2.48 500 3.45 480 180 32 ✔ ✔ Color Hardness Specific Gravity Compression Set @ 23°C Compression Set @ 100°C 100% Modulus 300% Modulus Tensile Strength Elongation Tear Strength ISO 10993 USP VI Special Characteristics ASTM Shore A ASTM/ISO ASTM % ASTM % ASTM psi Mpa ASTM psi Mpa ASTM psi ISO Mpa ASTM % ASTM pll ISO kN/m GENERAL PROPERTIES TENSILE PROPERTIES OTHER For further information on specific grades, review technical data sheets.

Versaflex™ HC and Versaflex™ HC BIO Thermoplastic Elastomers TPEs for Biopharmaceutical Tubing (BT) The Versaflex™ HC and Versaflex™ HC BIO BT series is formulated specifically to handle the complexities of biopharma tubing. Delivering on critical application demands, it provides weldability, kink resistance, and tensile strength performance comparable to leading medical tubing materials, including silicone and TPE. Offering reliable performance, optical clarity and expanded design freedom, these medical- grade TPEs may be customized to meet specific regulatory demands or application needs.

These TPEs have good processability. Silicone tubing is very expensive. Medical grade SBC compounds have transparent or translucent appearance and are suitable for medical tubing applications.

CPAP Tubing Film Medical Tubing Medical Tubing

CHARACTERISTICS TPE THERMOSET RUBBER LIM* SILICONE PVC Compression Set Good Excellent Excellent Fair Heat Resistance Good Excellent Excellent Fair UV/Ozone Resistance Good Good Good Good Chemical Resistance Good Excellent Excellent Good Barrier Properties Excellent Good Excellent Excellent # of Manufacturing Steps Excellent Good Good Excellent Supply Chain Availability Excellent Excellent Fair Excellent Colorability Excellent Good Good Excellent Total Costs $$ $$$ $$$$ $ THERMOPLASTIC ELASTOMERS FOR HEALTHCARE GENERAL CHARACTERISTICS COMPARING TPE, RUBBER, SILICONE, AND PVC We offer a broad range of TPEs solutions that are specially formulated to meet demanding healthcare device and application challenges. Common applications include medical device overmolds, medical and biopharma tubing, and gaskets and stoppers. PP OVERMOLDING HARDNESS REGULATORY STERILIZATION CHARACTERISTICS Dynaflex™ G2706 28A USP Class VI, ISO 10993, Food contact EtO Soft translucent grade, grippy feel Dynaflex™ G2711 43A USP Class VI, ISO 10993, Food contact EtO Highly colorable solution, grippy feel, low compression set Versaflex™ CL2242 & CL2250 42A/ 50A USP Class VI, ISO 10993, US Food contact EtO Clear boilable grades; ABS, PC bondable Versaflex™ G2705 N 60A USP Class VI, ISO 10993, Food contact EtO/Steam High resilience, low compression set Versaflex™ HC3810 20A-90A USP Class VI, ISO 10993 EtO General purpose, unfilled ABS, PC OVERMOLDING HARDNESS REGULATORY STERILIZATION CHARACTERISTICS Versaflex™ OM1040 40A USP Class VI, ISO 10993 EtO Translucent Versaflex™ OM3060 60A USP Class VI, ISO 10993 EtO Clear VERSAFLEX™ CL AND DYNAFLEX™ TPEs OVERMOLDING FOR ERGONOMICS • Adds good tactile surface with soft-touch feel • Available in a variety of color effects and textures • Improves grip, cushion, and comfort • Enhances functional performance like sealing properties, vibration damping, oxygen barrier, and scratch and abrasion resistance • Reduces assembly costs, good processability • Offers excellent adhesion to a wide range of substrates Applications: • Glucometers • Medical tools overmolds • Injector pens • Analysis devices VERSALLOY™ HC & VERSAFLEX™ HC TPEs SEALING & RESEALING • Rubbery feel and soft touch • No coring, good puncture, and resealability in static stoppers • Meets low coefficient of friction requirements in dynamic seals • Low extractables • Suitable to overmold onto polyolefins Applications: • Sealing and resealing septum • Seals and sanitary gaskets • Syringe plungers and tips MATERIAL DESCRIPTION HARDNESS REGULATORY STERILIZATION CHARACTERISTICS Versalloy™ HC 9210-45N 45A USP Class VI EtO Good processability, smooth surface aesthetics Versalloy™ HC 9210-55N 55A USP Class VI EtO Good processability, smooth surface aesthetics Versalloy™ HC 9210-70N 70A USP Class VI EtO Good processability, smooth surface aesthetics Versalloy™ HC 9220-43N 43A USP Class VI, ISO 10993-4/5 EtO Extrusion grade, high temperature resistance Versaflex™ HC 2110-35N 34A FDA, USP Class VI, ISO 10993 Autoclave EtO radiation Resealing, elevated comp set Versaflex™ HC 2110-57B 57A FDA, USP Class VI, ISO 10993 Autoclave EtO radiation Low stiction VERSAFLEX™ CL AND DYNAFLEX™ TPEs HIGH CLARITY GRADES WITHOUT PLASTICIZERS • Water clear grades formulated without phthalate plasticizers • Meets medical regulatory USP Class VI and ISO 10993-4,5 • Food contact and FDA compliant • Autoclave and radiation stable • Low extractable • High clarity (Haze 50 4.1, 100 4.5, 100 4, 70 6, 70 Tensile Modulus (MPa) 2200 2700 2600 2350 1820 1820 Flexural Strength (MPa) 80 90 104 86 68 68 Flexural Modulus (MPa) 2500 2700 2500 2300 1980 1590 HDT: 0.45, 1.8 (MPa) 110, 80 90, 80 100, 89 123, 100 123, 64 100, 70 UL-94 Rating @ 3.0 mm 5VA V-0 5VA V-0 HB V-0 UL-94 Rating @ 1.5 mm V-0 V-0 5VB V-0 HB V-0 UL-94 Rating @ 0.75 mm V-1 V-2 V-0 None None V-2 COMPETITIVE MATERIAL COMPARISON ENGINEERED POLYMER FORMULATIONS FOR HEALTHCARE TRILLIANT™ HC THERMOPLASTICS The family of Trilliant™ HC high-performance thermoplastics is formulated to meet the growing challenges of medical devices and equipment.

SOLUTIONS FOR FIBER OPTIC CABLE Engineered Fibers, Color & Additives, Specialty Engineered Materials BINDER YARN Flat, low-profile Highly absorbent (up to 65x its weight) BUFFER TUBE SWELLABLE YARN Cleaner than gel Highly absorbent WATER SWELLABLE FRP Non-corrosive, non-conductive, No flaking or shedding Overcoat and upjacketing available STRENGTH MEMBER Aramid or fiberglass yarn Processes cleanly with minimal dust UNDER-SHEATH RIPCORD Swellable, non-wicking Available in colors for easy identificationLASER MARKING ADDITIVES Provide good contrast in black outer jacket for outdoor exposure JACKET Color formulations for PVC, PE, TPU, TPC UV protective additives Non-halogenated colors for LSFOH LSFOH UV formulations for high flame retardancy, chemical and UV resistance, low COF TPE Polyamide, custom polyolefins LOOSE TUBES, TIGHT BUFFERS AND MICRO-MODULES LSFOH UV formulations for improved processing speeds, strippability & gel resistance Customized formulations: PBT PP TPE Color formulations for polyamide, PBT, LSFOH , TPE, TPC (Thermoplastic Copolyester) Laser marking additives https://www.avient.com/products/fiber-line-engineered-fiber-solutions/fiber-line-engineered-fiber-products/ripcords-fiber-optic-cable https://www.avient.com/products/fiber-line-engineered-fiber-solutions/fiber-line-engineered-fiber-products/water-blocking-absorbing-yarn https://www.avient.com/products/fiber-line-engineered-fiber-solutions/fiber-line-engineered-fiber-products/water-blocking-absorbing-yarn https://www.avient.com/products/fiber-line-engineered-fiber-solutions/fiber-line-engineered-fiber-products/fiber-reinforced-polymer https://www.avient.com/products/fiber-line-engineered-fiber-solutions/fiber-line-engineered-fiber-products/strength-members https://www.avient.com/products/fiber-line-engineered-fiber-solutions/fiber-line-engineered-fiber-products/ripcords-fiber-optic-cable https://www.avient.com/products/polymer-additives/performance-enhancement-additives/oncap-laser-marking-additives https://www.avient.com/products/polymer-colorants/solid-color-masterbatches/oncolor-wire-cable https://www.avient.com/products/polymer-additives/uv-and-light-blocking-additives/oncap-uv-stabilizer-additives https://www.avient.com/products/polymer-colorants/solid-color-masterbatches/oncolor-wire-cable https://www.avient.com/products/engineered-polymer-formulations/eco-conscious-formulations/eccoh-low-smoke-and-fume-non-halogen-formulations https://www.avient.com/products/engineered-polymer-formulations/eco-conscious-formulations/eccoh-low-smoke-and-fume-non-halogen-formulations https://www.avient.com/products/thermoplastic-elastomers/onflex-thermoplastic-elastomers https://www.avient.com/products/engineered-polymer-formulations/general-engineered-formulations https://www.avient.com/products/engineered-polymer-formulations/eco-conscious-formulations/eccoh-low-smoke-and-fume-non-halogen-formulations https://www.avient.com/products/engineered-polymer-formulations/eco-conscious-formulations/eccoh-low-smoke-and-fume-non-halogen-formulations https://www.avient.com/products/engineered-polymer-formulations/general-engineered-formulations/bergadur-polyester-formulations https://www.avient.com/products/engineered-polymer-formulations/general-engineered-formulations https://www.avient.com/products/thermoplastic-elastomers/onflex-thermoplastic-elastomers https://www.avient.com/products/polymer-colorants/solid-color-masterbatches/oncolor-wire-cable https://www.avient.com/products/polymer-colorants/solid-color-masterbatches/oncolor-wire-cable https://www.avient.com/products/polymer-additives/performance-enhancement-additives/oncap-laser-marking-additives

As performance and aesthetics requirements increase, the demand for specialty TPE materials continues to grow. TPEs are becoming a integral part of each products brand experience. Your customers will feel the difference when you use our GLS™ TPEs to differentiate your next breakthrough product.

™ TPEs vs. TPEs vs. And in some case, the lower production costs of TPEs make them an economical alternative for many single-use products and pharmaceutical-grade delivery tubing.

MEDICAL TUBING EXTRUDER B I O P H A R M A C E U T I C A L T U B I N G • Low leachables & extractables • Great tensile performance and kink resistance • Good thermal weldability • Excellent clarity and medical blue tint • ISO 10993-4 & 5, USP Class VI & Animal Derivative Free (ADF) • Supplied drop-in material replacement to overcome supply constraints of incumbent TPE • Offered a lower extractable profile than comparable materials in the market • Enabled easy material transition without changes in tooling or thermal welding machine settings • Formulated solution with proprietary additives to provide clarity and prevent yellowing after sterilization Versaflex™ HC BT218 Thermoplastic Elastomer KEY REQUIREMENTS WHY AVIENT?